Kuzhithura (also known as Kuzhithurai) is a city and a municipality in Kanyakumari District in the Indian state of TamilNadu.

It is the administrative headquarters of the Vilavancode Taluk. It is located along the Kochi-Trivandrum-Kanyakumari National highway 47.

It has a historical seaport (thura or thurai) where ancient merchants came from across the Arabian sea in ancient times. It is mentioned in ancient Indian maps. As of 2011, the town had a population of 21,307.

Kuzhithura municipality spreads over an area of 5 km². The Thamiraparani river flows through Kuzhithura.

This town is famous for the annual Vavu Bali (Shradham for the ancestors held during the Mahalaya Amavasi) ceremony that is held here during July/Aug (Malayalam month Karkidakam).

The Government Higher Secondary School Vilavancode is situated at Kuzhithura junction. It was founded by HRH Sir Sree Chithira Thirunal, Maharajah of Travancore GCSI, GCIE (November 7, 1912 – July 19, 1991) who was the last ruling Maharaja of the princely state of Travancore.